Two and a Half Men
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| Award | Year (↓) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| MediaVillage TV Fan Award | 2006 | Outstanding Comedy Series | Nominee | |
| MediaVillage TV Fan Award | 2006 | Outstanding Actor in a Comedy Series | Nominee | Jon Cryer |
| MediaVillage TV Fan Award | 2006 | Outstanding Actor in a Comedy Series | Nominee | Charlie Sheen |
| Emmy Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| Internet TV Award | 2006 | Favorite Actor in a Primetime Comedy Series | Nominee | Charlie Sheen |
| Young Artist Award | 2006 | Best Performance by a Supporting Young Actor in a Television Comedy Series | Winner | Angus T. Jones |
| Emmy Award | 2006 | Outstanding Guest Actor in a Comedy Series | Nominee | Martin Sheen |
| BMI TV Music Award | 2005 | Winner | Chuck Lorre | |
| Emmy Award | 2005 | Outstanding Multi-Camera Picture Editing for a Series | Nominee | Joe Bella |
| Emmy Award | 2005 | Outstanding Multi-Camera Sound Mixing for a Series or Special | Winner | Bruce Peters; Kathy Oldham; Bob La Masney; Charlie McDaniel |
| GLAAD Media Award | 2005 | Outstanding Individual Television Episode | Nominee | |
| ASCAP Film & TV Music Award | 2005 | Top Television Series | Winner | Lee Aronsohn; Grant Geissman |
| Emmy Award | 2005 | Outstanding Art Direction for a Multi-Camera Series | Nominee | John Shaffner; Ann Shea |
| Mr. Skin's Anatomy Award | 2005 | Best Network TV Scene | Winner | Kristin Dattilo |
| Cadet Award | 2005 | Outstanding Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| Emmy Award | 2005 | Outstanding Cinematography for a Multi-Camera Series | Nominee | Steve Silver |
| Viewers Voice Award | 2005 | Favorite Half-Hour Show | Nominee | |
| Viewers Voice Award | 2005 | Favorite Supporting Actress in a Comedy | Nominee | Holland Taylor |
| Screen Actors Guild Award | 2005 | Outstanding Performance by an Actor in a Television Comedy Series | Nominee | Charlie Sheen |
| Emmy Award | 2005 | Outstanding Supporting Actress in a Comedy Series | Nominee | Holland Taylor |
| Emmy Award | 2005 | Outstanding Supporting Actress in a Comedy Series | Nominee | Conchata Ferrell |
| Cadet Award | 2005 | Outstanding Supporting Actress in a Comedy Series | Nominee | Conchata Ferrell |
| Golden Globe Award | 2005 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Charlie Sheen |
| Parents Television Council Award | 2005 | Worst Family Shows on Primetime Network TV (#7) | Winner | |
| RATTY Award | 2005 | Best Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| Cadet Award | 2005 | Top 12 Scenes or Lines | Winner | |
| TV Times Readers' Choice | 2005 | Best Actor in a Comedy (#3) | Voted | Charlie Sheen |
| Artios Award | 2005 | Best Casting for an Episodic Comedy Series | Nominee | Nikki Valko; Ken Miller |
| SHINE Award | 2004 | Scene Stealer | Nominee | |
| ASCAP Film & TV Music Award | 2004 | Top Television Series | Winner | Lee Aronsohn; Grant Geissman |
| Artios Award | 2004 | Best Casting for a Comedy Pilot | Nominee | Nikko Valko; Ken Miller |
| TV Times Readers' Choice | 2004 | Best Actor in a Comedy (#4) | Voted | Charlie Sheen |
| TV Times Readers' Choice | 2004 | Best Comedy Series (#5) | Voted | |
| Emmy Award | 2004 | Outstanding Art Direction for a Multi-Camera Series | Nominee | |
| BMI TV Music Award | 2004 | Winner | Chuck Lorre | |
| RATTY Award | 2004 | Best Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| Young Artist Award | 2004 | Best Performance by a Young Actor (Ten or Under) in a Television Comedy or Drama Series | Winner | Angus T. Jones |
| RATTY Award | 2004 | Best Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| Emmy Award | 2004 | Outstanding Cinematography for a Multi-Camera Series | Nominee | Steven V. Silver |
| Internet TV Award | 2004 | Favorite Actor in a Primetime Comedy Series | Nominee | Charlie Sheen |
| Young Artist Award | 2004 | Best Family Television Comedy or Drama Series | Nominee | |
| People's Choice Award | 2004 | Favorite New Television Comedy Series | Winner | |
| RATTY Award | 2004 | Best New Series | Nominee | |
| about.com Primetime TV Awards | 2004 | The Freshman Award | Nominee | |
| TV Guide Award (televised) | 2004 | Favorite Comedy Star | Nominee | Charlie Sheen |
| Parents Television Council Award | 2004 | Worst Family Shows on Primetime Network TV (#4) | Winner | |
| Emmy Award | 2004 | Outstanding Main Title Theme Music | Nominee | Chuck Lorre; Lee Aronsohn; Grant Geissman |
