Malcolm in the Middle
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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Emmy Award | 2002 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2002 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2002 | Outstanding Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Emmy Award | 2002 | Outstanding Guest Actress in a Comedy Series | Nominee | Susan Sarandon |
| Emmy Award | 2002 | Outstanding Directing for a Comedy Series | Nominee | Jeff Melman |
| Emmy Award | 2001 | Outstanding Guest Actor in a Comedy Series | Nominee | Robert Loggia |
| Emmy Award | 2001 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2001 | Outstanding Comedy Series | Nominee | |
| Emmy Award | 2001 | Outstanding Multi-Camera Sound Mixing for a Series or Special | Nominee | |
| Emmy Award | 2001 | Outstanding Writing for a Comedy Series | Winner | Alex Reid |
| Emmy Award | 2001 | Outstanding Directing for a Comedy Series | Winner | Todd Holland |
| Emmy Award | 2001 | Outstanding Directing for a Comedy Series | Nominee | Jeff Melman |
| Emmy Award | 2001 | Outstanding Lead Actor in a Comedy Series | Nominee | Frankie Muniz |
| Emmy Award | 2001 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2000 | Outstanding Writing for a Comedy Series | Winner | Linwood Boomer |
| Emmy Award | 2000 | Outstanding Casting for a Comedy Series | Nominee | |
| Emmy Award | 2000 | Outstanding Directing for a Comedy Series | Winner | Todd Holland |
| Emmy Award | 2000 | Outstanding Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2000 | Outstanding Guest Actress in a Comedy Series | Nominee | Beatrice Arthur |
| Electronic Media's Critics Poll | 2002.01 | Best Television Series (#5) | Winner | |
| Electronic Media's Critics Poll | 2001.07 | Best Television Series (#3) | Winner | |
| Electronic Media's Critics Poll | 2001.01 | Best Television Series (#2) | Winner | |
| Electronic Media's Critics Poll | 2000.07 | Best Television Series (#3) | Winner | |
| Directors Guild Award | 2002 | Outstanding Directorial Achievement in Television Comedy Series | Winner | Todd Holland |
| Directors Guild Award | 2001 | Outstanding Directorial Achievement in Television Comedy Series | Nominee | Todd Holland |
| Commie Award | 2003 | Funniest TV Actress | Nominee | Jane Kaczmarek |
| Commie Award | 2003 | Funniest TV Wife | Winner | Jane Kaczmarek |
| Commie Award | 2003 | Funniest TV Series | Nominee | |
| Cadet Award | 2005 | Outstanding Directing in a Comedy Series | Nominee | Linwood Boomer |
| Cadet Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Laurie Metcalf |
| Cadet Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Betty White |
| Cadet Award | 2003 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Cadet Award | 2003 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Cadet Award | 2003 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Cadet Award | 2003 | Outstanding Writing in a Comedy Series | Nominee | |
| Cadet Award | 2002 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Cadet Award | 2002 | Outstanding Guest Actress in a Comedy Series | Winner | Susan Sarandon |
| Cadet Award | 2002 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Cadet Award | 2002 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Cadet Award | 2001 | Outstanding Comedy Series | Nominee | |
| Cadet Award | 2001 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Cadet Award | 2001 | Outstanding Supporting Actor in a Comedy Series | Nominee | Justin Berfield |
| Cadet Award | 2001 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Cadet Award | 2001 | Outstanding Guest Actor in a Comedy Series | Winner | Robert Loggia |
| Cadet Award | 2001 | Outstanding Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Cadet Award | 2001 | Outstanding Writing in a Comedy Series | Nominee | Ian Busch |
| Cadet Award | 2001 | Outstanding Directing in a Comedy Series | Nominee | Todd Holland |
| Cadet Award | 2000 | Outstanding Comedy Series | Nominee | |
| Cadet Award | 2000 | Outstanding Debut Series | Nominee | |
| Cadet Award | 2000 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
