Malcolm in the Middle
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| Award | Year (↑) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Cadet Award | 2005 | Outstanding Directing in a Comedy Series | Nominee | Linwood Boomer |
| Online Television Academy Award | 2005 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Writers Guild Award | 2005 | Best Writing in an Episodic Comedy Series for Television | Winner | Neil Thompson |
| Young Artist Award | 2005 | Best Performance by a Recurring Young Actor in a Television Comedy or Drama Series | Winner | Cameron Monaghan |
| Kids Choice Award | 2005 | Favorite TV Actor | Nominee | Frankie Muniz |
| Teen Choice Award | 2005 | Choice TV Actor in a Comedy Series | Nominee | Frankie Muniz |
| Online Television Academy Award | 2005 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2005 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2005 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| TV Times Readers' Choice | 2005 | Best Actress in a Comedy (#5) | Voted | Jane Kaczmarek |
| Emmy Award | 2006 | Outstanding Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Writers Guild Award | 2006 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| Emmy Award | 2006 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2006 | Outstanding Choreography | Nominee | Fred Tallaksen |
| MediaVillage TV Fan Award | 2006 | Outstanding Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| MediaVillage TV Fan Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| TelevisionWeek's Best of 25 Years | 2007 | Broadcast's Best of Past 25 Years | Winner | |
| Writers Guild Award | 2007 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| AOL Television All Time Lists | 2008 | TV's 50 Best Comedies of All Time (#42) | Winner | |
| EW's All Time Greatest/Worst Lists | 2008 | 100 New TV Classics (#88) | Winner |
