Malcolm in the Middle
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| Award | Year (↓) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| AOL Television All Time Lists | 2008 | TV's 50 Best Comedies of All Time (#42) | Winner | |
| EW's All Time Greatest/Worst Lists | 2008 | 100 New TV Classics (#88) | Winner | |
| TelevisionWeek's Best of 25 Years | 2007 | Broadcast's Best of Past 25 Years | Winner | |
| Writers Guild Award | 2007 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| Emmy Award | 2006 | Outstanding Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Writers Guild Award | 2006 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| Emmy Award | 2006 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2006 | Outstanding Choreography | Nominee | Fred Tallaksen |
| MediaVillage TV Fan Award | 2006 | Outstanding Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| MediaVillage TV Fan Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2005 | Outstanding Music and Lyrics | Nominee | Charles Sydnor; Eric Kaplan |
| Cadet Award | 2005 | Outstanding Directing in a Comedy Series | Nominee | Linwood Boomer |
| Online Television Academy Award | 2005 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Writers Guild Award | 2005 | Best Writing in an Episodic Comedy Series for Television | Winner | Neil Thompson |
| Young Artist Award | 2005 | Best Performance by a Recurring Young Actor in a Television Comedy or Drama Series | Winner | Cameron Monaghan |
| Kids Choice Award | 2005 | Favorite TV Actor | Nominee | Frankie Muniz |
| Teen Choice Award | 2005 | Choice TV Actor in a Comedy Series | Nominee | Frankie Muniz |
| Online Television Academy Award | 2005 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2005 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2005 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| TV Times Readers' Choice | 2005 | Best Actress in a Comedy (#5) | Voted | Jane Kaczmarek |
| Teen Choice Award | 2004 | Choice TV Actor in a Comedy Series | Nominee | Frankie Muniz |
| Emmy Award | 2004 | Outstanding Choreography | Nominee | Fred Tallekson |
| RATTY Award | 2004 | Best Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Kids Choice Award | 2004 | Favorite TV Actor | Winner | Frankie Muniz |
| Young Artist Award | 2004 | Most Popular Mom & Dad in a Television Series | Nominee | Jane Kaczmarek |
| Young Artist Award | 2004 | Most Popular Mom & Dad in a Television Series | Nominee | Bryan Cranston |
| Golden Laurel Award | 2004 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Writers Guild Award | 2004 | Best Writing in an Episodic Comedy Series for Television | Nominee | Gary Murphy, Neil Thompson |
| Writers Guild Award | 2004 | Best Writing in an Episodic Comedy Series for Television | Nominee | Dan Kopelman |
| Emmy Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| American Choreography Award | 2004 | Outstanding Choreography in Episodic Television | Winner | Fred Tallaksen |
| Online Television Academy Award | 2004 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Online Television Academy Award | 2004 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Golden Satellite Award | 2004 | Best Actress in a Television Comedy or Musical Series | Winner | Jane Kaczmarek |
| Emmy Award | 2004 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| TV Guide Award (televised) | 2004 | Favorite Comedy Star | Nominee | Jane Kaczmarek |
| Cadet Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Laurie Metcalf |
| Cadet Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Betty White |
| Teen Choice Award | 2004 | Choice TV Comedy Series | Nominee | |
| Online Television Academy Award | 2004 | Best Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Golden Satellite Award | 2004 | Best Actor in a Television Comedy or Musical Series | Nominee | Bryan Cranston |
| Commie Award | 2003 | Funniest TV Actress | Nominee | Jane Kaczmarek |
| Screen Actors Guild Award | 2003 | Outstanding Performance by an Actress in a Television Comedy Series | Nominee | Jane Kaczmarek |
| Commie Award | 2003 | Funniest TV Wife | Winner | Jane Kaczmarek |
| Cadet Award | 2003 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Teen Choice Award | 2003 | Choice TV Actor in a Comedy Series | Nominee | Frankie Muniz |
| Internet TV Award | 2003 | Favorite Primetime Comedy Series | Nominee | |
| Emmy Award | 2003 | Outstanding Single-Camera Picture Editing for a Comedy Series | Winner | Mark Scheib, Steve Welch |
