Will & Grace
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| Award | Year (↓) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| TV Guide Award (televised) | 2001 | Favorite Supporting Actress in a Comedy Series | Nominee | Megan Mullally |
| Cadet Award | 2001 | Outstanding Lead Actress in a Comedy Series | Nominee | Debra Messing |
| Emmy Award | 2001 | Outstanding Writing for a Comedy Series | Nominee | Jeff Greenstein |
| Online Television Academy Award | 2001 | Best Guest Actor in a Comedy Series | Winner | Patrick Dempsey |
| Hollywood Makeup Artist & Hair Stylist Guild Award | 2001 | Best Period Makeup in a Television Series | Nominee | Patty Bunch, Karen Kawahara |
| Directors Guild Award | 2001 | Outstanding Directorial Achievement in Television Comedy Series | Winner | James Burrows |
| GLAAD Media Award | 2001 | Outstanding Television Comedy Series | Winner | |
| Online Television Academy Award | 2001 | Best Direction in a Comedy Series | Winner | |
| RATTY Award | 2001 | Best Supporting Actress in a Comedy Series | Nominee | Megan Mullally |
| Online Television Academy Award | 2001 | Best Writing in a Comedy Series | Winner | |
| Emmy Award | 2001 | Outstanding Art Direction for a Multi-Camera Series | Winner | Glenda Rovello, Melinda Ritz |
| Emmy Award | 2001 | Outstanding Casting for a Comedy Series | Nominee | Tracy Lilienfield |
| Cadet Award | 2001 | Outstanding Directing in a Comedy Series | Nominee | James Burrows |
| American Comedy Awards | 2001 | Funniest Lead Female Performer in a Television Series | Nominee | Debra Messing |
| American Comedy Awards | 2001 | Funniest Supporting Female Performer in a Television Series | Nominee | Megan Mullally |
| American Comedy Awards | 2001 | Funniest Supporting Male Performer in a Television Series | Winner | Sean Hayes |
| RATTY Award | 2001 | Best Guest Actor in a Comedy Series | Nominee | Woody Harrelson |
| Artios Award | 2001 | Best Casting for an Episodic Comedy Series | Nominee | Tracy Lilienfield |
| ALMA Award | 2001 | Outstanding Actress in a Television Series | Nominee | Shelley Morrison |
| Emmy Award | 2001 | Outstanding Cinematography for a Multi-Camera Series | Winner | Tony Askins |
| American Comedy Awards | 2001 | Funniest Guest Male Performer in a Television Series | Nominee | Gregory Hines |
| Online Television Academy Award | 2001 | Best Editing in a Television Series | Winner | |
| Wand Award | 2001 | Best Guest Star | Nominee | Debbie Reynolds |
| Golden Laurel Award | 2001 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| American Comedy Awards | 2001 | Funniest Television Series | Nominee | |
| Emmy Award | 2001 | Outstanding Costumes for a Series | Nominee | Lori Eskowitz-Carter |
| Wand Award | 2001 | Best Bitch | Winner | Karen |
| Emmy Award | 2001 | Outstanding Directing for a Comedy Series | Nominee | James Burrows |
| Online Television Academy Award | 2001 | Best Costume Design in a Television Series | Nominee | |
| Cadet Award | 2001 | Outstanding Costume Design | Nominee | |
| Wand Award | 2001 | Best Show | Nominee | |
| Online Television Academy Award | 2001 | Best Sound in a Television Series | Nominee | |
| Teen Choice Award | 2001 | Choice TV Actor | Nominee | Eric McCormack |
| Emmy Award | 2001 | Outstanding Multi-Camera Picture Editing for a Series | Nominee | Peter Chakos |
| Petcabus Award | 2001 | Best Comedy Series | Nominee | |
| Teen Choice Award | 2001 | Choice TV Actress | Nominee | Debra Messing |
| Online Television Academy Award | 2001 | Best Episode in a Comedy Series | Winner | |
| Online Television Academy Award | 2001 | Best Episode in a Comedy Series | Nominee | |
| Teen Choice Award | 2001 | Choice TV Sidekick | Winner | Sean Hayes |
| Teen Choice Award | 2001 | Choice TV Sidekick | Nominee | Megan Mullally |
| Petcabus Award | 2001 | Best Actor in a Comedy Series | Nominee | Eric McCormack |
| Golden Satellite Award | 2001 | Best Actor in a Television Comedy or Musical Series | Nominee | Sean Hayes |
| Petcabus Award | 2001 | Best Actress in a Comedy Series | Nominee | Debra Messing |
| Teen Choice Award | 2001 | Choice TV Comedy Series | Nominee | |
| Emmy Award | 2001 | Outstanding Lead Actor in a Comedy Series | Winner | Eric McCormack |
| Petcabus Award | 2001 | Best Supporting Actor in a Comedy Series | Nominee | Sean Hayes |
| Viewers Voice Award | 2001 | Favorite Supporting Actor in a Comedy Series | Nominee | Sean Hayes |
| Emmy Award | 2001 | Outstanding Lead Actress in a Comedy Series | Nominee | Debra Messing |
| Screen Actors Guild Award | 2001 | Outstanding Performance by an Actor in a Television Comedy Series | Nominee | Sean Hayes |
| Screen Actors Guild Award | 2001 | Outstanding Performance by an Actress in a Television Comedy Series | Nominee | Debra Messing |
