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| Award | Year (↓) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Online Television Academy Award | 2001 | Best Guest Actor in a Drama Series | Winner | James Cromwell |
| TV Guide Award (televised) | 2001 | Favorite Supporting Actress in a Drama Series | Nominee | Maura Tierney |
| RATTY Award | 2001 | Best Guest Actor in a Drama Series | Winner | James Cromwell |
| Online Television Academy Award | 2001 | Best Guest Actress in a Drama Series | Winner | Sally Field |
| RATTY Award | 2001 | Best Guest Actress in a Drama Series | Winner | Sally Field |
| RATTY Award | 2001 | Best Ensemble in a Drama Series | Nominee | |
| Ammy Award | 2001 | Best Actress in a Television Production | Nominee | Ming-Na |
| Wand Award | 2001 | Best Wedding Proposal | Winner | Mark to Elizabeth |
| Wand Award | 2001 | Biggest Downturn | Nominee | |
| PRISM Award | 2001 | Outstanding Multi-Episode Storyline in a Television Drama Series | Winner | |
| ALMA Award | 2001 | Outstanding Actress in a Television Series | Nominee | Laura Ceron |
| Golden Laurel Award | 2001 | Norman Felton Producer of the Year for Episodic Drama Television | Nominee | |
| Wand Award | 2001 | Best Guest Star | Winner | Sally Field |
| NAACP Image Award | 2001 | Outstanding Actor in a Drama Series | Nominee | Eriq La Salle |
| Emmy Award | 2001 | Outstanding Directing for a Drama Series | Nominee | Jonathan Kaplan |
| BMI TV Music Award | 2001 | Winner | Martin Davich | |
| NAACP Image Award | 2001 | Outstanding Supporting Actress in a Drama Series | Nominee | Michael Michele |
| Cadet Award | 2001 | Outstanding Sound | Nominee | |
| People's Choice Award | 2001 | Favorite Television Drama Series | Winner | |
| Golden Reel Award (MPSE) | 2001 | Outstanding Editing of Dialogue and Automated Dialogue Replacement (A.D.R.) in Episodic Television | Nominee | |
| Golden Reel Award (MPSE) | 2001 | Outstanding Sound Editing in Episodic Television | Nominee | |
| Petcabus Award | 2001 | Best Actress in a Drama Series | Nominee | Maura Tierney |
| Screen Actors Guild Award | 2001 | Outstanding Performance by an Actor in a Television Drama Series | Nominee | Anthony Edwards |
| Screen Actors Guild Award | 2001 | Outstanding Performance by an Actress in a Television Drama Series | Nominee | Sally Field |
| Screen Actors Guild Award | 2001 | Outstanding Performance by an Ensemble in a Television Drama Series | Nominee | |
| Emmy Award | 2001 | Outstanding Supporting Actress in a Drama Series | Nominee | Maura Tierney |
| RATTY Award | 2001 | Most Declined Series | Nominee | |
| Banff Rockie Award | 2001 | Best Continuing Series | Nominee | |
| Electronic Media's Critics Poll | 2000.07 | Best Television Series (#20) | Winner | |
| Electronic Media's Critics Poll | 2000.01 | Best Television Series (#17) | Winner | |
| RATTY Award | 2000 | Worst Actress on Television | Nominee | Kellie Martin |
| RATTY Award | 2000 | Worst Actress on Television | Winner | Michael Michele |
| Emmy Award | 2000 | Outstanding Sound Mixing for a Drama Series | Nominee | |
| ASCAP Film & TV Music Award | 2000 | Top Television Series | Winner | James Newton Howard |
| TeeVee Award | 2000 | Worst Actor | Winner | Erik Palladino |
| Online Television Academy Award | 2000 | Best Drama Series | Nominee | |
| TeeVee Award | 2000 | Worst Hour Show | Winner | |
| Golden Laurel Award | 2000 | Vision Award for Television | Winner | |
| RATTY Award | 2000 | Best Drama Series | Nominee | |
| Golden Globe Award | 2000 | Outstanding Television Drama Series | Nominee | |
| Online Television Academy Award | 2000 | Best Lead Actress in a Drama Series | Winner | Julianna Margulies |
| Writers Guild Award | 2000 | Best Writing in an Episodic Drama Series for Television | Nominee | John Wells |
| RATTY Award | 2000 | Best Ensemble in a Drama Series | Nominee | |
| Online Television Academy Award | 2000 | Best Supporting Actor in a Drama Series | Winner | Noah Wyle |
| Golden Globe Award | 2000 | Outstanding Actress in a Television Drama Series | Nominee | Julianna Margulies |
| Online Television Academy Award | 2000 | Best Ensemble Cast in a Drama Series | Nominee | |
| RATTY Award | 2000 | Best Lead Actor in a Drama Series | Nominee | Anthony Edwards |
| RATTY Award | 2000 | Best Lead Actor in a Drama Series | Nominee | Noah Wyle |
| RATTY Award | 2000 | Best Lead Actress in a Drama Series | Nominee | Julianna Margulies |
| TV Times Readers' Choice | 2000 | Best Drama Series (#1) | Voted |
