Prison Break
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| Award (↑) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Teen Choice Award | 2006 | Choice TV Actor | Nominee | Wentworth Miller |
| Teen Choice Award | 2006 | Choice TV Sidekick | Nominee | Amaury Nolasco |
| Television Critics Association Award | 2006 | Outstanding New Program of the Year | Nominee | |
| TelevisionWeek's Critics Poll | 2006.02 | Best Television (#19) | Winner | |
| TelevisionWeek's Critics Poll | 2006.01 | Best Television (#7) | Winner | |
| Time Magazine's Best/Worst List | 2005 | Top Ten Best Television Shows (#9) | Winner | |
| Tubey Award | 2007 | The Best Way to Visit Europe Without Leaving Home or Flipping on the Travel Channel Award | Winner | |
| Tubey Award | 2006 | Show with the Most HoYay (#3) | Voted |
